Skip to main content
Fig. 6 | Cell Division

Fig. 6

From: Klotho-mediated activation of the anti-oxidant Nrf2/ARE signal pathway affects cell apoptosis, senescence and mobility in hypoxic human trophoblasts: involvement of Klotho in the pathogenesis of preeclampsia

Fig. 6

Klotho regulated oxidative damages and cell mitosis in PE rat models in vivo. A ELSIA was used to examine Klotho concentrations in PE rats’ serum. The mRNA and protein levels of Klotho in PE rats’ placental tissues were respectively determined by performing B Real-Time qPCR and C Western Blot analysis. D The MDA levels and E GSH/GSSG ratio in PE rats’ placental tissues were determined by their commercial kits. F The expression levels of total Nrf2, SOD2 and NQO1 in PE rats’ placental tissues were determined by conducting Western Blot analysis. Real-Time qPCR was employed to examined the mRNA levels of G CDK2, H CDK6 and I Cyclin D1 in rats’ placental tissues. Each experiment was repeated at least for three times, and *P < 0.05 was considered as statistical significance. Each experiment was repeated at least for three times

Back to article page

Cell Division

ISSN: 1747-1028

Contact us